刘锐，博士研究生, 中山大学博士后研究员，南方学院高层次引起人才

学术兼职：广东省抗癌协会肿瘤代谢专委会委员，广东省精准医学应用学会代谢头颈肿瘤专委会委员，广州新特克药物研究有限公司高级技术顾问，深圳泓瑞康泽生物医药科技有限公司资深研究员

教育背景

(1) 2018-09 至 2022-06, 中山大学, 博士

(2) 2013-09 至 2017-04, 温州医科大学, 硕士

(3) 2007-09 至 2011-06, 南方医科大学, 学士

教研成果

发表国际高水平SCI期刊论文多篇，以第一或共一作者中科院1区SCI论文3篇，2项研究成果已完成成果转化。主持国家和省部级自然科学基金项目2项，参与国家科技重大专项和国家重点研发计划、多项省部级重点项目。2017年学术论文获评浙江省优秀硕士学位论文，研究项目获得阿斯利康横向资助。

近五年代表性研究论文：

(1) Rui Liu^#; Panpan Liu^#; Huichang Bi; Jianhua Ling; Huiqin Zhang; Mingquan Zhang; Yumin Hu; Paul J Chiao; Peng Huang*; Jinyun Liu*; Malignant transformation by oncogenic K‐ras requires IDH2‐mediated reductive carboxylation to promote glutamine utilization, Cancer Communications, 2022, 43(2): 285-289 (期刊论文，中科院一区，IF 20.1)

(2) Rui Liu^#; Jiajia Tang^#; Chaodong Ding; Weicheng Liang; Li Zhang; Tianke Chen; Yan Xiong; Xiaowei Dai; Wenfeng Li; Yunsheng Xu; Jin Hu; Liting Lu; Wanqin Liao; Xincheng Lu*; The depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades, Cancer Letters, 2017, 390(1): 48-57 (期刊论文，中科院一区，IF 9.1)

(3) Junchen Pan^#; Rui Liu^#; Wenhua Lu^#; Hongyu Peng; Jing Yang; Qianrui Zhang; Tiantian Yu; Bitao Huo; Xiaoying Wei; Haixi Liang; Lin Zhou; Yameng Sun; Yumin Hu; Shijun Wen; Jie Fu; Paul J.Chiao; Xiaojun Xia; Jinyun Liu; Peng Huang*; SQLE-catalyzed squalene metabolism promotes mitochondrial biogenesis and tumor development in K-ras-driven cancer, Cancer Letters, Epub 2025 Feb 25 (期刊论文，中科院一区，IF 9.1)

(4) Daqian Zhu^#; Jiadi Li; Meiling Le; Rui Liu; Bingling Luo; Yameng Sun; Peng Huang; Xiaohui Cao*; Shijun Wen*; Substrate and Catalyst Cocontrolled Regioselective and Chemo-Switchable Annulation of Unsymmetric Cyclic AryIiodoniums, ACS Catalysis, Epub 2025, 15(4): 2927-2938 (期刊论文，中科院一区，IF 11.3)

(5) Panpan, Liu^#; Yao, Luo^#; Hongyu, Wu; Yi, Han; Shoujie, Wang; Rui, Liu; Shijun, Wen; Peng, Huang*; HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2, CELL DEATH AND DIFFERENTIATION, 2024, 31(12): 1595-1610 (期刊论文，中科院一区，IF 13.7)